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   Nose cell transplant enables paralysed dogs to walk. This has great potential for helping human spinal cord injuries in the future. Bonus: Test conducted on "real life" injuries, not laboratory animals

19 Nov 2012 11:01 AM   |   5344 clicks   |   BBC
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gopher321    [TotalFark]  
The nose knows.

19 Nov 2012 08:11 AM
Counter_Intelligent     
I didn't think this could be possible. I even hate looking at dachshunds' x-rays.

19 Nov 2012 08:40 AM
Cythraul     
This is good news. Hopefully it'll translate well into treatments for humans. Good news, good news.

19 Nov 2012 08:48 AM
Friskya     
Even better is, since the "real life" injuries were not likely to have been recent injuries, it's probable that further research will show that the age of the injury has no bearing on the efficacy of the treatment. It might take a little longer for the treatment to be fully effective, but this is far more than having no hope at all.

Good news, for people and pets.

19 Nov 2012 09:19 AM
xanadian    [TotalFark]  
Your dog will run a marathon for steak.

19 Nov 2012 11:04 AM
Incontinent_dog_and_monkey_rodeo     
But how does he smell?

19 Nov 2012 11:04 AM
Bit'O'Gristle     
I've got good news, we can fix your blindness, but we have to go in through your anus.

19 Nov 2012 11:04 AM
Eddie Adams from Torrance    [TotalFark]  
i236.photobucket.comView Full Size


Approves.

19 Nov 2012 11:07 AM
dv-ous     
YAY!! WALKING DOG!!! WHEEE!!!!

YOU GUY LITTLE GUY!

I'm sorry - this was the neatest thing I've seen in a while and I'm now in a completely awesome mood.

19 Nov 2012 11:10 AM
dv-ous     
Err... "You go, little guy!"

I blame chiclet keyboards.

19 Nov 2012 11:11 AM
Clemkadidlefark     
Pretty interesting. Hope it's true.

19 Nov 2012 11:12 AM
calm like a bomb     
I DNRTFS, but many dogs with complete transaction can over time develop the ability to do what's called spinal walking. I wonder how they accounted for that.

/why yes, I did do a fellowship in spinal cord injury

19 Nov 2012 11:13 AM
GungFu     
My dog has a nose cell transparent.
How does it smell?

Awful!

/My wife went on holiday.
Jamaica?
Nah, she wanted to go.

19 Nov 2012 11:14 AM
dervish16108     
Even if it doesn't work on humans, good for the dogs! I hope it works on humans too, though.

19 Nov 2012 11:24 AM
natazha     
As a former owner of a weenerdog that ruptured a disk, I'm cheered to see this. Rusty (and I) were lucky to live within driving distance of one of the best canine surgeons in the country, who was willing to operate at 11 p.m. on a Friday. Wasn't cheap, but he recovered fully.

19 Nov 2012 11:41 AM
ErinPac     

calm like a bomb: I DNRTFS, but many dogs with complete transaction can over time develop the ability to do what's called spinal walking. I wonder how they accounted for that.

/why yes, I did do a fellowship in spinal cord injury


In the journal linked, it looks like they also did a trial with 6 humans.
They can test sensory response below the injury, as well as document changes in MRI's. Of course, there was also a control group (received an inert injection and treadmill treatments without the particular cells), which presumably would also have the possibility of learning spinal walking - that's exactly the sort of thing you'd expect to filter out by comparison to a control.

19 Nov 2012 12:09 PM
Pardon Me Sultan     

Eddie Adams from Torrance: [i236.photobucket.com image 672x451]

Approves.


Came here to post this; glad to see the efficiency of Fark remains undiminished.

19 Nov 2012 12:10 PM
Newt13     
Read the headline as,..."Test conducted on "real life" injuries, not labrador animals.

Go Science!

19 Nov 2012 12:12 PM
Friskya     

ErinPac: Of course, there was also a control group


I hope they went back and offered the control group the legitimate treatments.

"Yes, we've got a treatment. No, you can't have it." would just suck.

19 Nov 2012 12:24 PM
Therion    [TotalFark]  
{csm}

In the early years of heart transplant surgery, the first "necessary" transplant surgery was performed on my cousin's dog.

{/csm}

19 Nov 2012 12:43 PM
ErinPac     

Friskya: ErinPac: Of course, there was also a control group

I hope they went back and offered the control group the legitimate treatments.

"Yes, we've got a treatment. No, you can't have it." would just suck.


Well, I doubt that statement would have quite the same depressing effect on dogs. I guess it'd suck for their owners. Really, while yes, sad poor puppy... some dogs seem to do a lot, happily, on their little robo-puppy wheels. I think they tend to adapt better than people *generally*.

Usually a control group (especially for people) still gets the best current care; it's not like they just are doomed. In some experiments, that's the 'good' group - decent care, save money, and less risk. Maybe their owners can spend more on treats and toys if they're paying less vet bills.

19 Nov 2012 01:54 PM
bmxfelon420     
As a disabled person, I hope this moves forward. I'd like them to do this on older injuries, as i've been injured for 10 years and most trials for new treatments want injuries within the past year. I see why, fresh injuries have a better chance of improving, but even just a small amount of regained function would be nice. (not sexual function, that's still good...giggety.)

19 Nov 2012 02:31 PM
jmsvrsn     

Incontinent_dog_and_monkey_rodeo: But how does he smell?

Terrible.

19 Nov 2012 02:48 PM
crabsno termites     
Came to find out what a human with dog nose cell transplant might look like.

/leaving disappoint.

//Come, JoJo.

19 Nov 2012 04:36 PM
bitchqueen     
All typical Fark snarkiness aside, that is freaking awesome

19 Nov 2012 05:15 PM
Pert     
Jesus........ The possibilities were endless..

"What happens when you inject a paralysed dog with nose cells? It runs...."
"How does he smell?"

etc.

OK... Two, TWO possibilities, but I refuse to believe that this was the best headline.

19 Nov 2012 05:23 PM
KrispyKritter     
laboratory animals is sick, sad and unnecessary. a great big Fu(k You to the ACLU. willing volunteer prisoners used to well serve these needs. there is no reason to torture little kritters.

/i hate people

19 Nov 2012 06:24 PM
Phins     
calm like a bomb: I DNRTFS, but many dogs with complete transaction can over time develop the ability to do what's called spinal walking. I wonder how they accounted for that.

What is "spinal walking" and how do the dog's develop the ability? Is there some sort of training or is it something biological that happens with some dogs?

I volunteer for a large rescue group and we get a lot of injured animals. We've had a few with paralyzed back legs. One was able to regain the ability to walk after surgery. I don't remember the exact nature of the surgery but I know it was highly specialized.

He was a chihuahua, brought in as a stray. He had apparently been on his own for a while, dragging his back half around. He had a large chest and front legs but scrawny back legs. He was like those guys who spend two hours a day weight lifting but never work their legs.

19 Nov 2012 06:33 PM
Friskya     

Phins: What is "spinal walking" and how do the dog's develop the ability? Is there some sort of training or is it something biological that happens with some dogs?


Spinal walking.

19 Nov 2012 07:29 PM
coldblades     

KrispyKritter: laboratory animals is sick, sad and unnecessary. a great big Fu(k You to the ACLU. willing volunteer prisoners used to well serve these needs. there is no reason to torture little kritters.

/i hate people


A quick glance at the leading researcher's CV shows publications using rats, collaborators using mice, and I'd be willing to bet large sums that this technique was tested in laboratory animals, possibly dogs, with induced injuries, before in pets with old injuries.

If anyone thinks that this achievement and others in the medical field aren't made possible by absolutely necessary laboratory animal experimentation and testing, they are horribly naive/ignorant.

/And I understand people think its fun to joke about using prison inmates for research, but if one honestly believes that testing on incarcerated humans is more ethical than animals.... yikes.

20 Nov 2012 08:20 AM
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